Fundamental, Research

2025 Big Pharma Outlook Reveals Risks and Opportunities for Biopharma Investors

Sel Hardy, Senior Vice President, Equity Research

Navigating Big Pharma's Shifting Landscape in 2025

The pharmaceutical sector is at a critical inflection point. CFRA’s latest outlook highlights mounting policy risks, rising geopolitical tensions, and shifting regulatory dynamics that are placing pressure on valuations—just as blockbuster drugs approach major patent cliffs. At the same time, innovation remains alive through AI-driven drug discovery and targeted M&A strategies.

In this in-depth research presentation led by Sel Hardy, CFRA’s Senior Vice President of Equity Research, we examine key forces shaping the future of biopharma—from the Inflation Reduction Act and MFN pricing reforms to the Section 232 tariff investigation that could significantly impact supply chains.

Preview highlights from the full video below, then access the complete research deck and video to uncover CFRA’s top biopharma picks and what may lie ahead for investors.

What Topics Are Covered:

  • Why CFRA downgraded the 12-month outlook for pharmaceuticals to Negative
  • The financial and strategic impact of the Inflation Reduction Act on drug pricing
  • Implications of the Section 232 Tariff Investigation on U.S. pharmaceutical supply chains
  • How M&A activity is driving portfolio growth amidst looming patent expirations
  • The transformative role of artificial intelligence in drug discovery
  • Which companies CFRA sees as best positioned for long-term success

Unlock the full slide deck and access the complete 13-minute expert video to gain CFRA’s latest biopharma sector insights and strategic picks for 2025.